On Friday evening, Evo-Stik League South, East side Cambridge City take on neighbouring St Neots Town at St Ives Town.
Saturday`s ties begin with a 12.30 kick-off where Bostik Premier side Billericay Town host Evo-Stik League South, West outfit Didcot Town which is being shown live on the BBC Sport website.
It really would be an upset if the Railwaymen were to beat a team containing the likes of England full international Paul Konchesky and under-21 star Jermaine Pennant amongst others.
Tividale, who took a voluntary drop down to the Step 6 West Midlands (Regional) League, face a two-division gap when they host Evo-Stik South, East side AFC Rushden & Diamonds, who knocked out former landlords Wellingborough Town in the Preliminary Round.
An interesting local derby sees Spartan South Midlands outfit Berkhamsted entertain Evo-Stik League South Premier Slough Town, while another derby takes place at Bostik North Potters Bar Town, who tackle Evo-Stik South Premier side Bishop`s Stortford, who haven`t won in five league games since suffering relegation from the Vanarama National League South last season.
Stortford’s League rivals, Kings Langley, take a trip across to Suffolk to play Thurlow Nunn Leaguers Haverhill Borough.
Step 6 South West Peninsula League Premier outfit Tavistock AFC take on Evo-Stik South, West high-flyers Taunton Town at Langsford Park.
Uhlsport Hellenic League Premier Division Tuffley Rovers will take on Taunton`s league rivals Swindon Supermarine.
Sunday sees Evo-Stik South side Romulus, who are yet to win a league game, hosting Evo-Stik South Premier side Kettering Town – who have won all of theirs – on the 3G at Coles Lane whilst Evo-Stik South, East newcomers Thame United go to Baldock Town.
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